Genetski modifikovane T celije potencijalni lek protiv ALL leukemijeCitat:
A new cancer therapy using patients’ own modified white blood cells to target cancer cells and remain in the body to protect it from future cancer tumor growth has scientists saying the breakthrough is “unprecedented in medicine.”
The news unfolded at the Annual Meeting of the American Association for the Advancement of Science (AAAS 2016) in Washington, DC, with three international leaders in the field of cancer research: Prof. Dirk Busch of the Technical University of Munich (TUM), Prof. Chiara Bonini of the San Raffaele Scientific Institute, and Prof. Stanley Riddell of the Fred Hutchinson Cancer Research Center.
In one study presented at the meeting, 94% of study participants with Acute Lymphoblastic Leukemia (ALL) had complete elimination of their symptoms after they were treated with the modified T-Cells.
In another study, more than 50% of participants with non-Hodgkin’s lymphoma were symptom free, while 80% of them had a positive response.
Lead scientist, Prof. Stanley Riddell told BBC, “”[The patients] were really at the end of the line in terms of treatment options and yet a single dose of this therapy put more than ninety percent of these patients in complete remission where we can’t detect any of these leukemia cells.”
Mali N, bice potrebno jos provera ali su inicijalni rezultati prilicno dobri. U jednoj od studija su pacijenti bez simptoma 2 godine.
Na zalost, trenutno se jos radi na eliminaciji potencijalno vrlo opasnih efekata koji su kostali zivota 2 pacijenta (prejak imunoloski odgovor organizma), ali uprkos tome i pogotovu uzevsi u obzir da su u pitanju terminalni pacijenti sa jako losim prognozama (bez daljih drugih opcija lecenja i na kraju zivota), rezultati su svakako vise nego obecavajuci.
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